The course is designed to study cell biology and the biochemistry of biological membranes and essential life processes disrupted in disease. The topics to be covered in this course include; structure and functioning of cell organelles, importance of bio membranes, organization of bio membranes, membrane proteins, structure, lipid composition, classification of integral lipids, membrane permeability, ATP powered pumps, ion channels, structure and properties of cytoskeletal elements; vesicular trafficking; secretory pathways and endocytic pathways, protein quality control, purification of organelles, membranes, sub-cellular fractionation of cells by differential centrifugation; purification of membrane proteins; Exploring essential cellular functions; biochemistry of cell cycle, cell survival and apoptosis, cell motility and differentiation, role of key signalling pathways, significance of disruption of essential cellular processes for diseases like cancer, neurodegeneration, cardiovascular disease, diabetes, and autoimmunity.
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