The course is designed to
study cell biology and the biochemistry of biological membranes and essential
life processes disrupted in disease. The topics to be covered in this course
include; structure and functioning of
cell organelles, importance of bio membranes, organization of bio membranes,
membrane proteins, structure, lipid composition, classification of integral
lipids, membrane permeability, ATP powered pumps, ion channels, structure and properties of cytoskeletal
elements; vesicular trafficking; secretory pathways and endocytic pathways,
protein quality control, purification of organelles, membranes, sub-cellular
fractionation of cells by differential centrifugation; purification of membrane
proteins; Exploring essential cellular functions; biochemistry of cell cycle,
cell survival and apoptosis, cell motility and differentiation, role of key
signalling pathways, significance of disruption of essential cellular processes
for diseases like cancer, neurodegeneration, cardiovascular disease, diabetes,
and autoimmunity.