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This course integrates concepts from chemistry, biophysics, electron microscopy and genetics to present the cell as the functional unit of life. Specific topics emphasized include organization and function of cellular organelles. The course describes intracellular components of both prokaryotic and eukaryotic cells. Other topics include; Biological molecules, replicons and DNA replication and recombination, gene expression and regulation in prokaryote and eukaryotes, operons, satellite DNAs, and protein synthesis and trafficking and signal transduction.