POG BSAG 1102: PRINCIPLES OF GENETICS

The course describes basic concepts of genetics; Significance of genetics in agriculture and Society. It also describes the Investigative approaches in genetics including cell division, and regulation of the cell cycle. Topics such as Spermatogenesis and oogenesis and principles of Mendelian genetics are also discussed. Other topics covered include; alleles; Sex-linked genes; Gene interaction; epistasis; Phenotypic expression: penetrance and expressivity temperature effects, nutritional effects; Heredity vs. environment; Linkage; linkage ratio; Incomplete linkage, single crossovers; Multiple crossovers; Chromosome mapping; Protein as the genetic material; RNA as the genetic material; Structure of DNA; Structure of RNA; Denaturation and Renaturation of nucleic acid; Molecular Hybridisation techniques; Viral and Bacterial chromosomes; Mitotic chromosomes; Polytene chromosomes; Mitochondria! DNA and heterochromatics are explored, including Mechanisms of sex determination; Variation; Molecular basis of mutation; population Genetics; and Physiological Genetics.