BIO BIOC 2101: BIOINFORMATICS

The course is designed to provide an introduction to Bioinformatics. Emphasis in this course will be put on topics such as; Bit.Uncertainity, Entropy and information. Information in nucleotide and protein sequences. Information flow during gene expression. Genetic Code and translation as a noisy communication channel. Structure of protein coding genes. Relational databases. Boolean expressions. Genome browsers. Comparative programming. Progressive multiple alignment. Weight matrices. Heuristics methods(BLAST). Machine learning techniques (PSI-BLAST). Molecular evolution.

Phylogenetic analysis. Trees. Phenetics and cladistics. Bayes theorem.