CBMP BIOC 1101: CHEMISTRY OF BIOMOLECULES AND METABOLIC PATHWAYS

The course is designed to provide a basis for understanding the chemistry of biomolecules and metabolic pathways of importance in clinical practice and research. Emphasis in this course will be put on Biochemical processes. Water. Non-covalent bonding, pH. Acids, bases and buffers. Amino acids. Protein structures. Enzyme catalysis. Enzyme kinetics. Lipids: structure and function. Carbohydrates, their structure and function. General overview and strategy of metabolism. Glycolysis. Minor pathways of carbohydrate metabolism. Gluconeogenesis. Glycogen metabolism. Regulation of carbohydrate metabolism. Pentose phosphate pathway. Citric acid cycle. Electron transport chain.

Oxidative phosphorylation. Fatty acid metabolism.

Ketone bodies. Nitrogen metabolism. Integration metabolism. Relevant case studies.