The course is designed to provide an in-depth description of the molecular basis of cancer. Topics to emphasize include; Cancer. Viruses and Cancer. Oncogene transduction. Compare voncs with c-oncs. Functional division of oncoproteins (overview). Oncoproteins. Non-receptor tyrosine kinases. G-protein (oncs). Serine/Threonine kinases. SH2 and SH3 domains common features and specificity. Nuclear Oncoproteins.
Anti-oncoproteins/Tumour suppressor proteins.
Detailed consideration of Low MW GTPases: Rho Proteins, Ras proteins, Rab Proteins.- Enrolled students: No students enrolled in this course yet