This course unit is designed to provide an introduction to the biochemistry of neurotransmission in the central nervous system. Topics of emphasis in this course will include; structure and function of neurons and glia. Basic anatomy of the central nervous system (CNS). Information transfer in CNS. The molecular basis of the action potential, neurotransmission and synaptic function. The molecular basis of neurotransmission release, examination of the key proteins involved in the process. Neurotransmitter classification and description of the major neurotransmitters and their localization function, receptors, and transporters. Neurotransmitter transporters: structure and function. Neurotransmitter receptors: structure and function. Detailed consideration of neurotransmission by acetylcholine, serotonin, glutamate and GABA. Key defects in neurotransmitter signalling that lead to brain malfunction for example in stroke, Parkinson’s disease, depression, and psychiatric disorders.
- Teacher: Ismail Turyatemba
- Enrolled students: No students enrolled in this course yet